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Posted by Alan F. Bachrach, M.D. on 02:49:50 2004/02/22
In Reply to: Re: Dr. Vinik's Discussion on Diabetes Station posted by Martin
Obviously, I do not have access to the data or the drug. However, as a physician, I have drug rep's walk into my office everyday trying to get me to prescribe drugs that had a statistically significant benefit in a research trial, but had no clinically significant benefit (I discussed this in a previous post, but will repeat my little explanation of the difference between the two if you need/want). I think if there was a real clinical benefit from INGAP we wouldn't need large numbers of subjects to know it and it would be obvious pretty early on. We would have heard about it by now. Instead, I think that the pharmeceutical company is hoping to find a statistical difference between the treated and untreated groups and this will allow them to market the drug to those of us who are desperate. All of this is conjecture and opinion on my part. I do send 500 dollars per year to help support Vinik's research, so I have that much hope/faith in his approach. However, I am becoming less optomistic as time wears on.
Alan
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