Posted by Ellen on October 31, 2001 at 19:39:55:
This may be aimed for type 2, but it's nice to see the drug companies looking at islet cells for treatment.
United States Patent Application 20010025023
Kind Code A1
Carr, Richard David September 27, 2001
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Inhibition of beta cell degeneration
Abstract
Methods for preventing beta cell degeneration, such as necrosis or apoptosis of beta cells in a subject, comprising administering a DPP-IV inhibitor to a subject in need thereof. The invention furthermore relates to a method for increasing the number and/or the size of beta cells. The invention also relates to a method for delaying the progression of Impaired Glucose Tolerance (IGT) to type 2 diabetes, as well as a method for delaying the progression of non-insulin demanding type 2 diabetes to insulin-demanding type 2 diabetes.
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Inventors: Carr, Richard David; (Vaerlose, DK)
Correspondence Name and Address: NOVO NORDISK OF NORTH AMERICA, INC
405 LEXINGTON AVENUE
SUITE 6400
NEW YORK
NY
10017