Posted by timmichalak@hotmail.com on February 08, 2001 at 14:39:03:
In Reply to: Latest results with Islet Sheets in dogs posted by Scott R. King on February 08, 2001 at 13:59:26:
Good job with these sheets!!! I can't wait to see the results when islets are encapsulated
Dr. Ricordi as always contended that all cells shed antibodies which are small enought to get through encapsulation devices.
These antigens attract antibodies.
Do these antigens pose a challenge in keeping the sheet free of fibrosis? If the encapsulated cells are porcine, would the hyperacute attack of the antigens pose problems to the sheet?
I hope not, but thought that I would ask.
Thanks